Chronic case of hypertrophic lichen planus treated successfully with oral acitretin by Dr Rameshwar Gutte

A 48 year old otherwise healthy married male, presented with multiple highly itchy dark raised
lesions over bilateral legs since 15 years. (Figure-1) Patient was treated with oral antihistamines
and topical moisturizers and topical steroid –salicylic acid ointments and intralesional steroid
injections by various dermatologists in past with only temporary relief. Based on history and
clinical examination, differential diagnosis of hypertrophic LP and prurigo nodularis was
With informed consent, biopsy was taken from a fresh representative lesion. Biopsy was
suggestive of lichen planus. (Figure-2a) (Figure-2b) On clinicopathological correlation a final
diagnosis of hypertrophic LP was made. Considering long standing nature of disease and various
treatments tried in past patient was explained about acitretin as treatment option and he was
started on acitretin 25mg twice daily along with oral hydroxyzine 25mg and topical moisturisor
and clobetasol and 6% salicylic acid ointment. He was advised to follow up after 2 weeks with
repeat tests for lipid profile and liver profile.
After 2 weeks patient noted around 30-40% improvement in lesions and some became flat. Also
itching was reduced. His lipid and liver profile showed no abnormality. Acitretin 25mg bid and
antihistamines were continued along with moisturizer for another 2 weeks. Since patient
tolerated acitretin well without any major side effects, except for mucosal dryness and slight hair
loss, it was continued for another 1 month. At the end of 2 months there was almost 90%
improvement with most of the lesions going flat. (Figure-3) We tapered acitretin to 25mg per
day, which was continued for another 2 months without any alterations in lipid and liver profile
on repeat tests. After total of 4 months acitretin was stopped and moisturizer was continued.

Source: Dr. L H Hiranandani Hospital


  • Abeyumowoi

    mebeverine manufacturers in india tenze24-domperidone can i take painkillers with buscopan

  • Ankutemav

    the far side cartoons buscopan before or after food

  • Akahoimim

    acth stimulation test results aliment anti brulure d estomac

  • Amuhefupoq

    what is schedule h1 drug medicine to reduce vomiting

  • Ayohomuney

    increase my milk supply fast order domperidone how quickly does zantac work for babies

  • Atasasodat

    best nighttime cold medicine can you take zyrtec

  • Ariwadzuhia

    fairness cream for black skin how to induce breast milk without being pregnant

  • Apodzubutay

    metoclopramide dosage for dogs list of otc companies in india

  • Arenokizot

    treatment of infant reflux acid reflux and nausea

  • Awanrasen

    pantosec d for acidity 1 m hcl solution

  • Ababakiwan

    causes of elevated prolactin levels domperidone buy online home remedies for the hiccups

  • Atosahirun

    ways to avoid snoring cetirizine dihydrochloride side effects

  • Afusezowor

    how to dry up milk supply without getting mastitis buy domperidone online what is ranitidine hcl 150mg tab used for

  • Adaesuzam

    baby noises while sleeping prilosec for infant reflux

  • Abiapemai

    breastfeeding husband for pleasure gripe water 2 week old

  • Apitokowau

    medication to induce lactation myo inositol indian brands

  • Ateruzahaz

    increase my milk supply can a woman lactate if she’s not pregnant

  • Asumeredab

    adenoma ipofisario intervento video enaltec labs ambernath maharashtra

  • Azosayodzug

    does sudafed cause dry mouth what is protonix used for

  • Agomedzubub

    eyes rolling back medical term mugijie29-domperidone is omeprazole an antibiotic

  • Aheseniheo

    nexium side effects headache order domperidone online symptoms of delayed gastric emptying

  • Aanajisej

    bladder spasms after uti mugijie post viral gastroparesis treatment


Leave a Reply

Português Português हिन्दी हिन्दी العربية العربية 简体中文 简体中文 Nederlands Nederlands English English Français Français Deutsch Deutsch Italiano Italiano Русский Русский Español Español